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Click here for the function of ACSS2. Edit this page in Wiki Genes - ACSS2 or see Wiki Gene. ACS participates in PPRC payment reform activities. Paper-7134457. In conclusion, cTnI and cTnT provide similar information in ACS. Paper-8847351. ACSL5 enhanced cell survival through its ACS catalytic activity. Paper-13567773. The expression levels of CD31 were increased in a small portion of the ACS patients. Paper-2156585. We conclude that the ACS BR assay is a fast and reliable immunoassay for measuring PEM in serum. Paper-973486. There is solid scientific data justifying the routine screening of women as proposed by the ACR and ACS. Paper-5714385. The RSS consists of the access control system ( ACS) and the radiation containment system (RCS). Paper-9123381. Deacetylation of AceCS2 by SIRT3 activates the acetyl-CoA synthetase activity of AceCS2. Paper-12058618. A new spectrophotometric method for quantitation of acetyl-CoA synthetase ( ACAS) activity is developed. Paper-13223259. Furthermore, cultured cells with benzbromarone added showed upregulated expression of LPL and ACS. Paper-13453018. Acyl-CoA synthetase 5 ( ACSL5) is a member of the ACS family, which converts fatty acid to acyl-CoA. Paper-13567773. Finally, the expression of PAI-1 mRNA was negatively correlated with mRNA of ACS present in both fat tissues. Paper-8941570. The ACS and SA genes probably derived from a duplication of an ancestral gene but have acquired different functions. Paper-8734918. Serum specimens were analyzed using the Hybritech Tandem R, Dianon Systems and Chiron ACS 180 free PSA assays. Paper-1509119. In the myocardium, mitochondrial acetyl-CoA synthetase ( ACSS1) mainly contributes to the radiopharmaceutical uptake. Paper-13966372. The PSA was over the RCDL of the ACS PSA assay in 15 of these patients and over the RCDL of the PSA2 assay in 2 patients. Paper-1056784. Finally, a 2.0-mm-diameter Hartzler LPS ( ACS) was utilized and successfully crossed and dilated 16 out of 31 lesions (52%). Paper-6010249. The analysis of the presteady- 1 Presented in part at the 173rd ACS National Meeting, New Orleans, L.A., U.S.A., March 20--25, 1977. Paper-2934717. Acyl-CoA synthetase 4 ( ACS4) is an arachidonate-preferring isozyme of ACS family predominantly expressed in steroidogenic tissues. Paper-9037436. The ACSA and PCSA VLO:VMO ratios in healthy and LPD subjects were 1.9:1.6 and 2.1:1.6, respectively (P = 0.025 and 0.202, respectively). Paper-13644902. [1-14C]Acetylcarnitine was prepared from [1-14C]acetate and L-carnitine using acetyl-CoA synthetase and carnitine acetyltransferase. Paper-7500771. IL-4 and IL-13 mRNA expression was suppressed in ACS subjects on topical steroid therapy compared to untreated patients. Paper-1088833. Triplicate measurements of PSA with the IMx ( Abbott) and the ACS 180 (Ciba Corning) were used to calculate the variance function. Paper-8227915. The single major difference of opinion between the PPRC and the ACS is related to the provision for a separate MVPS for surgical procedures. Paper-6788262. Digoxin-like immunoreactive factor (DLIF) in patients' sera was not detected in the ACS assay but was in the TDx, Stratus, and Magic assays. Paper-686285. RESULTS: The number of cells expressing IL-4 and IL-13 transcripts was significantly higher in subjects with ACS compared to normal controls. Paper-1088833. Addition of anti- G-CSF antibody (Ab) to ACS decreased CAFC recruitment significantly, whereas anti- IL-3 Ab had no significant effect. Paper-8542560. There were no patients whose PSA was less than the RCDL of the ACS PSA assay who had a measurable PSA level by any of the other assays. Paper-1056784. Clinical and technical evaluation of ACS BR serum assay of MUC1 gene-derived glycoprotein in breast cancer, and comparison with CA 15-3 assays. Paper-973486. A colorimetric assay method to measure acetyl-CoA synthetase activity: application to woodchuck model of hepatitis virus-induced hepatocellular carcinoma. Paper-13223259. Evaluation of a centrifuge with rapid turnaround time for the preparation of plasma samples for measurement of common STAT markers on the ACS: 180 system. Paper-8500892. Many of the objectives of both the PPRC and the ACS have been attained, and implementation of the reform measures will take place over the next five years. Paper-6788262. Acetyl-CoA synthetase (EC 6.2.1.1) and acyl-CoA synthetase (EC 6.2.1. 8) are ligases that synthesize p(4)A from ATP and P(3) and, to a lesser extent, Np(n)N. Paper-8520328. ACS 180 detected bb- PRL somewhat differently from the RIA-gnost and Delfia systems, but likewise most of the patients of group 2 had PRL values above normal. Paper-1868351. ACS patients had a higher proportion of isoforms < 26 K4 (low molecular weight) than SA patients (56/85 vs. 12/33, P < 0.005) and controls (10/29, P < 0.005). Paper-8927133. In the human heart, cytochrome c oxidase, acetyl-CoA synthetase, and myoglobin expression was increased in the failing heart and returned to normal with unloading. Paper-12221686. Patient samples tested on the ACS:180 cTnI assay showed good correlation with the Stratus cTnI assay ( ACS: cTnI = 1. 02*Stratus + 0.05 g/L, r = 0.96, n = 1170). Paper-8439827. The ACS will continue to play a significant role as an advisor to the PPRC as it defines and "fine tunes" medical policy recommendations for the Administration and Congress. Paper-6423858. This study demonstrates that ectopic expression of GIP-R is rare in AA and is usually associated with the low fasting plasma cortisol levels that characterize FD- ACS. Paper-9451654. Six different stent types (AVE Microstent-II, AVE-GFX, ACS Multi-link, JJ Palmaz-Schatz, JJ Crown, and NIR) were deployed in freshly excised porcine coronary vessels. Paper-9033979. These data indicate that the rupture of plaque and subsequent formation of thrombus may lead to the activation of CD40L expression in circulating platelets of ACS patients. Paper-2156585. IL-12R ( beta2) expression was decreased in ACS subjects as compared with control (P < 0.05), however, there was no significant difference found between NCS subjects and control. Paper-8289115. It has been applied for ACAS assay in the liver tissues of a woodchuck model of hepatitis virus- induced hepatocellular carcinoma ( HCC). Paper-13223259. We conclude that the automated assays for free DPD in urine, i.e. the HPLC and the ACS: 180 assay, show better analytical performance than the manual immunoassays studied. Paper-1536753. The finding suggests an increase in ACAS activity in the liver cancer of woodchuck models of HCC as compared to that in the normal woodchuck liver. Paper-13223259. The American Cancer Society/National Prostate Cancer Detection Project ( ACS/NPCDP) had a cancer detection rate of 2.4% for its initial year utilizing PSA, DRE and TRUS. Paper-7353157. Analysis of patterns of care of brain tumor patients in the United States: a study of the Brain Tumor Section of the AANS and the CNS and the Commission on Cancer of the ACS. Paper-6596096. The ACS is a clinical entity that develops from progressive, acute increases in IAP and affects multiple organ systems in a graded fashion because of differential susceptibilities. Paper-1571769. CONCLUSION: These in vitro studies suggest that ACS is able to increase matrix component production by human chondrocytes and to inhibit the negative effects of IL-1 beta. Paper-1503471. It specifically inhibits the enzyme activity of type 2 1-aminocyclopropane-1-carboxylate synthases ( ACC synthases or ACS) and promotes their degradation by a proteasome-dependent pathway. Paper-12246509. Knowledge of the ACS, however, is also essential for the management of critically ill pediatric patients (especially those with AWD) and in understanding the limitations of laparoscopy. Paper-1571769. Acetyl-CoA synthetase, acetyl-CoA hydrolase, and citrate synthase activities were present in cell-free extracts of C. cryptica, but did not change in response to 4 h of silicon deficiency. Paper-6092207. ACS did not influence cell viability, the expression of alpha 2 beta 1 integrin and cellular fibronectin, or the cytoskeletal organization of fibroblasts involving actin until 3 h. Paper-802495. Binding activity of PPARs with PPRE was determined by electric mobility shift assay, and expression of lipoprotein lipase ( LPL) and acyl-CoA synthetase ( ACS) by Western blot method. Paper-13453018. Whilst an increase in ACS4 expression has been associated with colorectal carcinogenesis, little is known about possible pathogenetic functions of other ACS isoforms, such as ACS5, in tumourigenesis. Paper-11239498. Most of these sequences were identified as ACS but three of them, belonging to the mammalian species, were annotated as another gene named: the SA gene, which is involved in the essential hypertension. Paper-8734918. It is anticipated that the ACS measures will figure significantly in the formal evaluation of the PCI, which will be carried out by an independent evaluator during the second and third years of the program. Paper-7488513. OBJECTIVES: To compare four assays-the Abbott IMx, the Tosoh, the Chiron ACS PSA, and the Chiron ACS PSA2-in their ability to detect prostate-specific antigen ( PSA) after radical prostatectomy. Paper-1056784. OBJECTIVE: To assess the detection of prostate cancer using the Ciba Corning ACS 180 prostate-specific antigen ( PSA) assay and transrectal ultrasonography (TRUS) in a district general hospital. Paper-958923. Regardless of whether ACSA or PCSA was used to predict resultant lateral force vectors, the values differed between healthy and LPD subjects ( approximately 2 and approximately 5.3 degrees , respectively; P < 0.05). Paper-13644902. Somatic and germ line inactivating mutations of PRKAR1 (regulatory subunit R1A of PKA) can be observed in patient with isolated primary pigmented nodular adrenocortical disease (PPNAD) and AA responsible for ACS. Paper-9604610. The expression of genes that regulate fatty acid availability in adipocytes, including lipoprotein lipase ( LPL) and acetyl-CoA synthetase ( ACS), was higher (P < 0.01) in pioglitazone-treated patients. Paper-10464067. The accumulated odds ratio (OR) for adverse events (30 days) in ACS with elevated cTnI (n = 5,759) and cTnT (n = 5,483) was 4.9 (95% confidence interval, CI, 3.9-6.2) and 4.6 (95% CI 3.8-5.5), respectively. Paper-8847351. Partial thromboplastin time (aPTT) was only slightly increased after ACS infusion (from 38.6+/-5.7 sec to 41.4+/-5.1 sec), but was significantly increased after HES infusion (from 38.7+/-5.7 sec to 46.1+/-7.0 sec). Paper-8614177. CONCLUSIONS: CAD patients with a history of ACS have higher Lp(a) plasma levels and a significantly higher proportion of low molecular weight apolipoprotein(a) isoforms compared with patients with SA or to controls. Paper-8927133. METHODS: We used a fully automated PSA assay system ( ACS: 180 assay) to evaluate a screening population of 814 men (mean age, 63.3 years; range, 50 to 79 years) without documented prostate cancer or prostate surgery. Paper-547816. We now cloned seven full-length and one near full-length cDNA representing four distinct 1-aminocyclopropane-1-carboxylic acid synthases ( ACS; ACS1, ACS2, ACS3, and ACS4) from spruce and Douglas fir. Paper-12397817. Because the activity of a bacterial ortholog of AceCS2, called ACS, is controlled via deacetylation by a bacterial sirtuin protein, our observation highlights the conservation of a metabolic regulatory pathway from bacteria to humans. Paper-12058618. ACSS1 and ACSS2 were highly expressed in a cell line with low (18)F-FDG uptake and high (11)C-acetate uptake, whereas only ACSS2 was expressed in a cell line with high (18)F-FDG uptake and low (11)C-acetate uptake. Paper-13913453. In the atrophied heart, respiratory chain and metabolic genes were down-regulated (NADH-DH, cytochrome c oxidase, acetyl-CoA synthetase, myoglobin) and cellular recognition and stress genes were up-regulated (MHC1 and 2, HSP70). Paper-12221686. When the C-terminal 14 amino acids (TOE; target of ETO1) of LE-ACS3 specific to type 2 ACC synthases were fused to a type 1 ACS, LE- ACS2, at the corresponding position, it allowed LE- ACS2 to strongly interact with LeEOL1. Paper-12246509. The system includes purified beta-ketothiolase (PhaA), NADPH-dependent acetoacetyl-CoA reductase (PhaB), PHA synthase (PhaC), acetyl-CoA synthetase ( Acs) and glucose dehydrogenase ( GDH). Paper-10957608. The effects of these agnets on cytoplasmic ATP-dependent citrate lyase, acetyl CoA synthetase and HMG-CoA reductase activities were reduced by a magnitude to explain the reduction of serum cholesterol levels afforded by the compounds. Paper-12793729. We performed a meta-analysis of published trials to determine the predictive value of cardiac troponin I (cTnI) and T ( cTnT) levels for adverse events (death and myocardial infarction) in acute coronary syndrome without ST elevation ( ACS). Paper-8847351. OBJECTIVE: To test the effects of chondroitin sulfate ( ACS, a glycosaminoglycan of cartilage) with and without interleukin-1 beta ( IL-1 beta) on human articular chondrocytes cultivated in clusters and in long-term (0-16 days or 16-32 days). Paper-1503471. Saethre-Chotzen syndrome (acrocephalo-syndactyly type III, ACS III) is an autosomal dominant craniosynostosis with brachydactyly, soft tissue syndactyly and facial dysmorphism including ptosis, facial asymmetry and prominent ear crura. Paper-829844. When CD34+ cell cultures were performed with ACS but without added interleukin-3 ( IL-3) and granulocyte colony- stimulating factor ( G-CSF), CAFC production was in the same range as if these growth factors were added alone. Paper-8542560. Sir2 proteins form a family of NAD(+)-dependent protein deacetylases required for diverse biological processes, including transcriptional silencing, suppression of rDNA recombination, control of p53 activity, regulation of acetyl-CoA synthetase, and aging. Paper-10390902. The initial and follow-up outcomes with the ACS Multi-Link stent (deployed from April to November 1995) were evaluated in 70 patients (79 lesions): unplanned in 34% (abrupt closure 1%; threatened closure 5%; suboptimal results 28%) and planned in 66%. Paper-1731621. During the first period (0-16 days), while the cluster is forming, ACS counteracted the IL-1 beta-induced effects on PG (500-1000 micrograms ACS/ml), coll-II (100-1000 micrograms ACS/ml) and PGE2 (500-1000 micrograms ACS/ml) productions. Paper-1503471. Choline acetyltransferase was a potent source of acetyl-CoA, only requiring acetylcholine and CoA, and was much more efficient than acetyl-CoA synthetase for concentrations of acetylcholine likely to be present in nerve endings. Paper-2857447. The results suggest the involvement of ACS5 in the early genesis of colorectal cancer, most likely by modification of the transport and pool formation of long-chain acyl-CoA thioesters, as recently demonstrated for other isoforms of the ACS family. Paper-11239498. During the second period (16-32 days), when the cluster is already formed, ACS counteracted the IL-1 beta-induced effects on total PG (100-1000 micrograms ACS/ml), coll-II (1000 micrograms ACS/ml) and PGE2 (1000 micrograms ACS/ml) productions. Paper-1503471. We have characterized a new, membrane-associated acyl-CoA synthetase ( ACS), termed bubblegum-related protein ( BGR), which upon functional analysis demonstrated ACS activity capable of activating long- and very long-chain fatty acids. Paper-12048830. The agents reduced acetyl CoA synthetase, ATP-dependent citrate lyase, acyl CoA cholesterol acyl transferase, sn-glycerol-3-phosphate acyl transferase activities of rat liver and small intestinal mucosa after 14 days treatment. Paper-12792874. In this system, acetyl-CoA was synthesized from acetate and CoA by Acs and ATP, and then two molecules of acetyl-CoA were condensed by PhaA to synthesize acetoacetyl-CoA, which was converted to (R)-3-hydroxybutyryl-CoA (3HBCoA) by PhaB and NADPH. Paper-10957608. This two-center human clinical trial evaluated recombinant human bone morphogenetic protein-2 delivered in an absorbable collagen sponge (rhBMP-2/ ACS) for either alveolar ridge preservation after tooth extraction or augmentation of localized osseous defects. Paper-1512196. Using gene-specific, quantitative real-time polymerase chain reaction, we measured constitutive expression for the four ACS genes and the single-copy ACO gene in various tissues of Sitka spruce ( Picea sitchensis) and in white spruce ( Picea glauca) somatic embryos. Paper-12397817. Dietary CLA increased the mRNA expression of PPAR gamma, fatty acid binding proteins (aP2), fatty acid transporter protein ( FATP), acyl-CoA synthetase ( ACS) and adiponectin in the adipose tissues of obese rats. Paper-12882228. Calculated rates for acetyl-CoA synthetase, acetyl-CoA carboxylase and malonyl-CoA-acyl-carrier protein transacylase reactions at the concentrations of metabolites measured here are < 0.1-4% of the observed rates of fatty acid synthesis from acetate by isolated chloroplasts. Paper-1222431. A maximum likelihood tree based upon the conserved regions showed that all sequences except the one from B. subtilis, belong to two basic groups: one the SA-like group including sequences from Archaeoglobus fulgidus and Streptomyces coelicolor, and second, the ACS group. Paper-8734918. They included hexokinase II, adenosine triphosphate citrate lyase, acetyl coenzyme A (CoA) synthetase 1 ( ACSS1), acetyl CoA synthetase 2 ( ACSS2), acetyl CoA carboxylase, and fatty acid synthase. Paper-13913453. The baseline peroxisome proliferator-activated receptor (PPAR)-gamma1 mRNA was significantly correlated with mRNA for LPL, CAP, ACS, 11beta HSD 1, GyK, fatty acid synthase, leptin, and GPDH, whereas PPAR-gamma2 mRNA was correlated with CAP, PEPCK-C, leptin, and GPDH. Paper-10464067. These findings suggest that ACS complemented with IL-3 and G-CSF replaces the accessory cells largely; this is not only due to presence of G-CSF, because ACS in combination with recombinant growth factors mounts CAFC yield higher than saturating amounts of growth factors alone do. Paper-8542560. Control of cortisol secretion by the abnormal expression of the gastric inhibitory polypeptide receptor ( GIP-R) have been observed in some rare cases of ACTH-independent, food-dependent Cushing's syndrome (FD- ACS) due to adrenal adenoma (AA) or bilateral macronodular hyperplasia (AIMAH). Paper-9451654. Exogenous ABA treatment increased the ABA content in both flesh and seed, inducing the expression of both ACS and ACO genes, and promoting ethylene synthesis and fruit ripening, while treatment with fluridone or nordihydroguaiaretic acid (NDGA) inhibited them, delaying fruit ripening and softening. Paper-13730962. The aim of this study was to compare the radial force of 17 coronary stents in vitro (Anglodynamics, ACS Multilink, AVE Micro II and GFX, Bard XT, Biocompatibles PC, Cook GR II, Cordis Crossflex, Hexacath Freedom, Johnson & Johnson PS 153'PS 154, and Crown, Medtronic Wiktor and BeStent BEL-15, Saint-Come SC 1616, Scimed Nir 7 and 9). Paper-1888496. The woodchucks were euthanized after imaging experiments and liver tissues were harvested for histology, for enzymatic activities including hexokinase ( HK), glucose-6-phosphatase, acetyl-CoA synthetase ( ACAS) and choline kinase ( CK), and for differential gene expressions between the HCCs and the surrounding hepatic tissues. Paper-13675579. In the present study, automated ( ACS: 180 DPD, Chiron Diagnostics, USA) and manual (DPD-ELISA, Pyrilinks-D, Metra Biosystems, USA) immunoassays for free DPD, and a manual immunoassay for the aminoterminal telopeptide of type I collagen (NTX, Osteomark, Ostex International, USA) were compared to the automated HPLC method for free DPD. Paper-1536753. To study the major metabolic pathways of imaging tracer [1-(11)C]-acetate in tumors for detection of HCC by Positron Emission Tomography (PET), the activity of one of the key enzymes involved in acetate or [1-(11)C]-acetate metabolism, ACAS was assayed by this newly developed assay in the tissue samples of woodchuck HCCs. Paper-13223259. These synonyms are used for gene ACSS2 (acyl-CoA synthetase short-chain family member 2): DKFZp762G026, dJ1161H23.1, Acyl-CoA synthetase short-chain family member 2, Acyl-activating enzyme, ACSA, ACS, Acetyl-coenzyme A synthetase, cytoplasmic, Acetyl-CoA synthetase, Acetate--CoA ligase, AceCS, ACAS2. These accession numbers are used for gene ACSS2: Q9UJ15 (UNIPROT__AC), Q5QPH2 (UNIPROT__AC), CAI19726 (NCBI_GENBANK__AC), AAH12172 (NCBI_GENBANK__AC). ACSS2 is a homologue of Os02g0525900 (Os02g0525900) from Oryza sativa Japonica Group. ACSS2 is a homologue of C36A4.9 (hypothetical protein) from Caenorhabditis elegans. ACSS2 is a homologue of AT5G36880 (acetyl-CoA synthetase, putative / acetate-CoA ligase, putative) from Arabidopsis thaliana. ACSS2 is a homologue of AgaP_AGAP006569 (AGAP006569-PA) from Anopheles gambiae str. PEST. ACSS2 is a homologue of ACSS2 (acyl-CoA synthetase short-chain family member 2) from Bos taurus. ACSS2 is a homologue of ACSS2 (acyl-CoA synthetase short-chain family member 2) from Pan troglodytes. ACSS2 is a homologue of ACSS2 (acyl-CoA synthetase short-chain family member 2) from Gallus gallus. ACSS2 is a homologue of ACSS2 (acyl-CoA synthetase short-chain family member 2) from Canis lupus familiaris. ACSS2 is a homologue of Acss2 (acyl-CoA synthetase short-chain family member 2) from Mus musculus. ACSS2 is a homologue of Acss2 (acyl-CoA synthetase short-chain family member 2) from Rattus norvegicus. ACSS2 is a homologue of acss2 (acyl-CoA synthetase short-chain family member 2) from Danio rerio. ACSS2 is a homologue of AcCoAS (Acetyl Coenzyme A synthase) from Drosophila melanogaster. Important links ! iHOP - Information Hyperlinked over Proteins . Concept & Implementation by Robert Hoffmann. |