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The lowest [ Gluc] during the IT identified the GT. Paper-12875755.
Uptake of LTC4 or E2- Gluc by human CMVs showed little inter-subject variability (2-5-fold). Paper-12005324.
Capillary blood glucose ( CBG) was determined hourly, and the insulin infusion rate was modified accordingly. Paper-12747251.
The EMR (prebreakfast CBG-midsleep CGB) was inversely related to the midsleep CBG level (r = -.45, P less than .001). Paper-5996360.
The crystal structure of human cytosolic beta-glucosidase unravels the substrate aglycone specificity of a family 1 glycoside hydrolase. Paper-13294977.
Uptake clearance among different species varied by approximately ten-fold (rat > dog = human > monkey) for LTC4 and less than two-fold for E2- Gluc. Paper-12005324.
The usual treatment group had a total of 87 CBG measurements of <or=3.6 mmol/l during the study, and only 1 such measurement (3.5 mmol/l) was recorded in the GLP-1 group. Paper-10137355.
There was no difference in mean intrapartum maternal CBG levels (103.9 +/- 8.7 mg/dL and 103.2 +/- 17.9 mg/dL in the rotating fluids and insulin drip group, respectively, P = .89). Paper-12244887.
CONCLUSIONS: The absorption of dietary flavonoid glycosides in humans involves a critical deglycosylation step that is mediated by epithelial beta-glucosidases ( LPH and CBG). Paper-9886941.
The results are in sharp contrast to those observed in human pregnancies in which both hSBP and hCBG are increased severalfold during pregnancy, including at term. Paper-3132502.
Uptake of [3H]-leukotriene C4 ( LTC4) and [3H]-estradiol-17beta-d-glucuronide ( E2- Gluc) was determined at a low substrate concentration and/or by kinetic measurements (K(m) and V(max)). Paper-12005324.
Correlation of in vitro data with in vivo findings was achieved by determining the biliary clearance of E2- Gluc in rats after a single i.v. dose and with literature in vivo data for LTC4. Paper-12005324.
Unlike klotho protein, it possesses neither a signal sequence nor a transmembrane domain, suggesting that it is a cytosolic protein, and thus was termed cytosolic beta-glucosidase-like protein-1 ( cBGL1). Paper-8555562.
Based on the substrate specificity of the human enzymes, sequence alignment of family 1 enzymes and analysis of the hCBG structural model, we selected and mutated putative substrate (aglycone) binding site residues. Paper-9920001.
Cytosolic beta-glucosidase (EC 3.2.1.21) from mammalian liver is a member of the family 1 glycoside hydrolases and is known for its ability to hydrolyse a range of beta-D-glycosides, including beta-D-glucoside and beta-D-galactoside. Paper-8982608.
The x-ray structure of KLrP at 1.6A resolution revealed that KLrP is a (beta/alpha)8 TIM barrel, in which Glu(165) and Glu(373) at the carboxyl termini of beta-strands 4 and 7 could function as an acid/base catalyst and nucleophile, respectively. Paper-12523113.
We recently reported the crystal structure of KLrP in complex with glucose [Y. Hayashi, N. Okino, Y. Kakuta, T. Shikanai, M. Tani, H. Narimatsu, M. Ito, Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase, J. Biol. Chem. 282 (2007) 30889-30900]. Paper-12908975.
CB with Giemsa ( CBG) revealed weak heterochromatic blocks in the telomeric regions of some chromosomes and conspicuous bands on the short arms of one chromosome pair, where nucleolar organizer regions (NORs) were evidenced by silver-staining. Paper-9815297.
To estimate the frequency of an early-morning glucose rise (EMR) in relatively unselected children with insulin-dependent diabetes mellitus ( IDDM), we assessed capillary blood glucose ( CBG) at midsleep (0200-0430) and prebreakfast (0700-0800) in 97 children with diabetes at camp. Paper-5996360.
Diabetic keto-acidosis (DKA) requires prompt diagnosis and all patients arriving emergency with dehydration, shock, coma, severe respiratory difficulty and evidence of any major illness should be tested for capillary blood glucose ( CBG) and urinary ketones urgently not to miss DKA. Paper-12280952.
Differences in in vitro uptake clearance (10-fold) between LTC4 and E2- Gluc in rat CMVs seemed to correlate with differences in their biliary clearance (4-fold) in rats, consistent with LTC4 and E2- Gluc being a high and a low clearance substrate, respectively. Paper-12005324.
When klotho and cBGL1 gene expression was examined in renal cell carcinoma tissues, both klotho and cBGL1 mRNA levels in tumors were lower than those in nontumor regions, suggesting that renal epithelial cells may lose klotho and cBGL1 gene expression during the course of malignant transformation. Paper-8555562.
These synonyms are used for gene GBA3 (glucosidase, beta, acid 3 (cytosolic)): MGC126878, MGC104276, KLrP, GLUC, Cytosolic beta-glucosidase-like protein 1, Cytosolic beta-glucosidase, CBGL1, CBG.
These accession numbers are used for gene GBA3: Q3MIH4 (UNIPROT__AC), A8K9N1 (UNIPROT__AC).
GBA3 is a homologue of zgc:112375 (zgc:112375) from Danio rerio.
GBA3 is a homologue of Os01g0508000 (Os01g0508000) from Oryza sativa (japonica cultivar-group).
GBA3 is a homologue of GBA3 (glucosidase, beta, acid 3 (cytosolic)) from Canis familiaris.
GBA3 is a homologue of GBA3 (glucosidase, beta, acid 3 (cytosolic)) from Pan troglodytes.
GBA3 is a homologue of Gba3 (glucosidase, beta, acid 3 (cytosolic)) from Rattus norvegicus.
GBA3 is a homologue of C50F7.10 (C50F7.10) from Caenorhabditis elegans.
GBA3 is a homologue of AT3G18080 (glycosyl hydrolase family 1 protein) from Arabidopsis thaliana.
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