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Hepatic GS, GDH and MAO showed a marked decrease in enzyme activity during parasitic infection. Paper-660365.
Thus, NH+4 formed via glutaminase (GLNase) could be distinguished from NH+4 formed via glutamate dehydrogenase ( GDH). Paper-1817223.
An N-terminal sequence of the 50 kDa adduct was 100% homologous with the deduced amino acid sequence of glutamate dehydrogenase. Paper-807061.
8. Glutamine metabolism is likely to occur via glutaminase and amino transaminase, which have significantly higher activities than glutamate dehydrogenase. Paper-7877344.
These decreases were consistent with an arrest in the developmental increase in SDH, LDH, and GDH at ages 31 +/- 0.6, 31 +/- 2.6, and 24 +/- 0.5 days, respectively. Paper-6466150.
For instance, alpha-KG formed from Glu by AspAT is reduced and aminated back to Glu by GDH, which oxidizes NADPH corresponding to the amount of alpha-KG formed. Paper-6487218.
Within the same samples and using similar techniques, we found that glutamine synthetase ( GS) and glutamate dehydrogenase ( GDH) expression were dramatically reduced. Paper-1047735.
1. Activity of glutamate dehydrogenase and adenylate deaminase were measured in the livers of carnivores (animals characterised by intake of a high dietary protein). Paper-4020338.
To fortify these alterations, elevation in the activities of aspartate aminotransferase (AAT), alanine aminotransferase (AlAT) and glutamate dehydrogenase ( GDH) were noticed. Paper-7907840.
The validity of the methods was tested by the distribution of cytosolic ( lactate dehydrogenase) and mitochondrial ( citrate synthase and glutamate dehydrogenase) marker enzymes. Paper-4694939.
Glutamate dehydrogenase activity was found to be present at a high level in neoplastic cytosol and microsomes, 3.45 and 9.90 nmoles NADH/min mg protein, respectively. Paper-3300955.
Chronic ethanol treatment via liquid diets from ages 20 to 55 days resulted in decreased activities of SDH and LDH at ages 40 and 44 days, and of GDH at ages 34, 40, and 44 days. Paper-6466150.
The activity of monoamine oxidase and phosphofructokinase increased by 105% (P < 0.02) and 41% (P < 0.05) respectively while glutamate dehydrogenase decreased by 15% (P < 0.001). Paper-7498973.
The activity of aconitase, a mitochondrial enzyme with an iron/sulfur cluster, is also significantly diminished (-50%), whereas glutamate dehydrogenase activity is unchanged. Paper-8893408.
The shift from glutamate consumption to glutamate production is correlated with an increase in glutamate dehydrogenase and glutamate oxaloacetate transaminase activity. Paper-1663354.
Recombination events between Tcr alpha/ CTLA-1 and the markers Gdh-X and NP-1 show that the most probable order of these loci in the mouse 14D region is NP-1- Tcr alpha/ Ctla-1- Gdh-X. Paper-5976010.
The decreased activity of FAD-linked glycerophosphate dehydrogenase contrasted with a normal activity of glutamate dehydrogenase and 2-ketoglutarate dehydrogenase in the islets of db/ db mice. Paper-7567740.
In the thin C57BL/6J mice, the activities of two alpha-glycerophosphate-generating enzymes i.e., glycerokinase ( GK) and alpha-glycerophosphate dehydrogenase ( GDH), increased in BAT at cold exposure. Paper-3090435.
No significant difference was demonstrated in the activities of GABA transaminase, glutamate dehydrogenase, lactate dehydrogenase, succinate dehydrogenase and NAD-malate dehydrogenase in any of the regions studied. Paper-3546032.
Protein profiles of amino acid metabolic enzymes suggest that accumulation of glutamine and glutamate in tissues of the aged SAMP8 may be due to hyperexpression of ornithine aminotransferase and/or glutamate dehydrogenase. Paper-10193874.
Moreover, we demonstrate that stimulation of CD11b(+) cells by GDH leads to the production of IL-6, IL-10 and B cell-activating factor ( BAFF), all of which combine to powerfully induce B cell expansion. Paper-12023186.
Progeny of an intersubspecies backcross were used to map one of these genes, Glud, proximal to Np-1 on Chromosome 14, but no restriction fragment polymorphisms could be identified for the second locus, Glud-2. Paper-34285.
The increase in photodamage is greater for the cytosolic and mitochondrial enzymes lactate dehydrogenase and glutamate dehydrogenase and least for the lysosomal enzymes beta-glucuroninidase and N-acetyl-beta-glucosaminidase. Paper-5653735.
Liver injury was mediated by the Fas/Fas ligand ( FasL) pathway and by perforin, because P14.gld and P14.PKO T cells failed to induce increased glutamate dehydrogenase levels despite strong in vivo proliferation. Paper-10405058.
Whereas most of these proteins have alanine at the N-terminal position, as observed for previously described antagonists, GdH has an N-terminal serine residue that is essential for X-linked IAP ( XIAP) interaction. Paper-12423216.
Acetylcholinesterase, glutamine synthetase, acid phosphatase and glutamate dehydrogenase activity in brain and cholinesterase activity in blood were investigated in mice exposed to 170 p.p.m. trichloroethylene (TCE) during 30 days. Paper-3919626.
In addition, this will provide the alpha-ketoglutarate carbon skeleton for glutamate and glutamine synthesis by glutamate dehydrogenase and glutamine synthetase ( astrocytes only), respectively, both reactions fixing ammonium. Paper-13316272.
In the one-step assay, both AT and GDH reactions are simultaneously carried out, and the decrease or increase in NADPH fluorescence is directly monitored in 1.0 ml of the reaction mixture for both forward and reverse reactions. Paper-6487218.
In GAD67-expressing astrocytes, the glutamate was mainly converted into GABA, suggesting GAD transgene activity to be dominant over other glutamate metabolic pathways, such as glutamine synthetase and glutamate dehydrogenase. Paper-1316751.
In particular, the enzymes glyceraldehyde 3-phosphate dehydrogenase ( G3PDH), lactate dehydrogenase (LDH), and glucose 6-phosphate dehydrogenase (G6PDH) bound to the GLUT1 3'-UTR while isocitrate dehydrogenase (IDH) and glutamate dehydrogenase (GluDH) did not. Paper-569369.
Lactate dehydrogenase, glucose phosphate isomerase and ( NADP) glutamate dehydrogenase were detected in all species; phosphogluconate dehydrogenase was detected in both Plasmodium species but malate dehydrogenase only in P. y. nigeriensis. Paper-3407819.
The severity of hepatitis was monitored histologically and by determination of changes in serum levels of the enzymes alanine aminotransferase ( ALT), aspartate aminotransferase ( AST), glutamate dehydrogenase ( GLDH), and alkaline phosphatase ( AP). Paper-5403793.
Treatment of H8 recipient mice with agonistic anti-CD40 Abs induced vigorous expansion of the transferred P14 T cells and led to liver cell destruction determined by increase of glutamate dehydrogenase serum levels and induction of caspase-3 in hepatocytes. Paper-10405058.
Enzyme analyses of culture medium and cell homogenates have detected some enzymes characteristic of liver tissue such as gamma-glutamyl transferase, sorbital dehydrogenase, alkaline phosphatase, glutamate dehydrogenase, as well as aspartate and alanine transaminase. Paper-5082235.
We have identified several additional potential IAP antagonists, including glutamate dehydrogenase ( GdH), Nipsnap 3 and 4, CLPX, leucine-rich pentatricopeptide repeat motif-containing protein and 3-hydroxyisobutyrate dehydrogenase. Paper-12423216.
In agreement with this observation, activities of the ammoniagenic enzymes, glutaminase and glutamate dehydrogenase, were not different in the renal cortex of fed and starved mice, but the glutamate dehydrogenase mRNA level was elevated 4.5-fold in the renal cortex from starved mice. Paper-9240101.
(2) The specific activities of carbamoyl-phosphate synthetase (ammonia) and glutamate dehydrogenase are about 15% lower than normal in mitochondria from spfash mice, whereas those of beta-hydroxybutyrate dehydrogenase and cytochrome oxidase are 22% higher and 30% lower respectively. Paper-6459136.
The enzymatic activities of glutamate decarboxylase (GAD), GABA aminotransferase ( GABA-T), alanine aminotransferase (ALA-T), aspartate aminotransferase (ASP-T), and glutamate dehydrogenase ( GDH) of whole brain supernatant are significantly reduced in these epileptic mice. Paper-8115411.
The enzymes concerned with glutamate metabolism (aspartate-, alanine- and tyrosine aminotransferases, glutamate dehydrogenase and glutamine synthetase) and (Na+ + K+)-ATPase were estimated in the three regions of brain (cerebellum, cerebral cortex and brain stem) and in liver. Paper-3367628.
The activities of another cytosolic enzyme, lactate dehydrogenase, the mitochondrial enzymes glutamate dehydrogenase, succinate dehydrogenase, cytochrome c oxidase and the activity of the lysosomal enzymes acid phosphatase and beta-glucuronidase were, initially, not or only slightly affected. Paper-5618334.
The ontogenetic development of the enzymes phosphate activated glutaminase (PAG), glutamate dehydrogenase ( GLDH), glutamic-oxaloacetic-transaminase (GOT), glutamine synthetase ( GS), and ornithine-delta-aminotransferase (Orn-T) was followed in cerebellum in vivo and in cultured cerebellar granule cells. Paper-5076406.
While glutamate dehydrogenase and alpha-ketoglutarate dehydrogenase complex activities are lower in the cerebellum and brain stem of the CD mouse, alanine aminotransferase and succinate semialdehyde dehydrogenase (SSADH) activities and succinate level are similar to the levels observed in the wild type. Paper-10387957.
Blood ammonia content and enzymes involved in ammonia metabolism, namely glutamine synthetase ( GS), glutamate dehydrogenase ( GDH), monoamine oxidase (MAO), alanine amino-transferase ( ALT) and aspartate aminotransferase (AST), were studied in Plasmodium yoelii-infected drug-treated mice tissues. Paper-660365.
Electrophoretic variation of the enzymes glucose phosphate isomerase, 6-phosphogluconate dehydrogenase, lactate dehydrogenase and glutamate dehydrogenase ( NADP-dependent) has been studied in the African murine malaria parasites Plasmodium berghei, P. yoelii, P. vinckei and P. chabaudi and their subspecies. Paper-3106880.
Alanine aminotransferase activity (ALA-T, E. C. 2.6.1.2), was not altered in any of the strains, and normalization of GAD, GABA-T and GDH activities by that of ALA-T, further revealed significant differences between the normal strain ( SPS/ SPS), the heterozygotes ( SPS/ sps), and behavioral arrest ( sps/ sps) mice. Paper-6820407.
The following approximative alloxan concentrations induced 50% inhibition of enzyme activity: 10(-6)M for aconitase, 10(-4)M for NAD-linked isocitrate dehydrogenase, glutamate dehydrogenase, alpha-ketoglutarate dehydrogenase, succinyl-CoA synthetase and fumarase, and 10(-3)M for citrate synthase and NADP-linked isocitrate dehydrogenase. Paper-4811075.
These synonyms are used for gene Glud1 (glutamate dehydrogenase 1): Glutamate dehydrogenase 1, mitochondrial, Gludl, Glud, Gdh-X, GDH, AI118167.
These accession numbers are used for gene Glud1: Q8C273 (UNIPROT__AC), Q3TSQ7 (UNIPROT__AC), BAC40767 (NCBI_GENBANK__AC), AAH57347 (NCBI_GENBANK__AC).
Glud1 is a homologue of ZK829.4 (hypothetical protein) from Caenorhabditis elegans.
Glud1 is a homologue of Os04g0543900 (Os04g0543900) from Oryza sativa Japonica Group.
Glud1 is a homologue of Os02g0650900 (Os02g0650900) from Oryza sativa Japonica Group.
Glud1 is a homologue of glud1b (glutamate dehydrogenase 1b) from Danio rerio.
Glud1 is a homologue of glud1a (glutamate dehydrogenase 1a) from Danio rerio.
Glud1 is a homologue of GLUD1 (glutamate dehydrogenase 1) from Homo sapiens.
Glud1 is a homologue of GLUD1 (glutamate dehydrogenase 1) from Bos taurus.
Glud1 is a homologue of GLUD1 (glutamate dehydrogenase 1) from Pan troglodytes.
Glud1 is a homologue of GLUD1 (glutamate dehydrogenase 1) from Gallus gallus.
Glud1 is a homologue of GLUD1 (glutamate dehydrogenase 1) from Canis lupus familiaris.
Glud1 is a homologue of Glud1 (glutamate dehydrogenase 1) from Rattus norvegicus.
Glud1 is a homologue of GDH2 (GDH2 (GLUTAMATE DEHYDROGENASE 2); ATP binding / glutamate dehydrogenase...) from Arabidopsis thaliana.
Glud1 is a homologue of Gdh (Glutamate dehydrogenase) from Drosophila melanogaster.
Glud1 is a homologue of AgaP_AGAP004362 (AGAP004362-PA) from Anopheles gambiae str. PEST.
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