Click here for the function of mreB.
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Just downstream of mreB, the mreC and mreD genes are located. Paper-12330012.
This suggests that mecillinam can be used very efficiently to select for found morphological mutants of rodA and envB after nitrosoguanidine treatment. Paper-3130400.
The mreC gene is preceded by the mreB gene and by a 65-base-pair spacing sequence containing a palindrome sequence and a possible Shine-Dalgarno sequence. Paper-1341.
Based on the sequence, it is suggested that the three mre genes (encoding the murein pathway), mreB, mreC and mreD, and these two ORFs possibly form an operon. Paper-45983.
They are also required for rod shape formation, though their role in chromosome segregation is unclear. lacZ fusion analysis and Northern hybridization showed that the mreB, mreC, and mreD genes formed an operon. Paper-12330012.
These are either the same or very close to the loci reported, respectively, for the rodA ( H. Matsuzawa, K. Hayakawa, T. Sato, and K. Imahori, J. Bacteriol. 115:436-442, 1973) and envB genes ( B. Westling-Häggström and S. Normark, J. Bacteriol. 123:75-82, 1975). Paper-3130400.
These synonyms are used for gene mreB (cell wall structural complex MreBCD, actin-like component MreB): rodY, mon, JW3220, envB, ECK3239.
These accession numbers are used for gene mreB: .
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Concept & Implementation by Robert Hoffmann.