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The DNase I sensitivity of Xenopus laevis genes transcribed by RNA polymerase III. Paper-4175995.
This raises the possibility that the La protein may be an RNA polymerase III transcription factor. Paper-11909421.
The intergenic distance between the 3' end of 128up mRNA and the 5' end of DmRP128 mRNA is only about 100 bp. Paper-114086.
Two transcription start points, seven nucleotides apart, are found for 128up compared to multiple scattered starts for DmRP128. Paper-114086.
Transcripts of 128up are present at a much higher level than DmRP128 RNA in Drosophila Schneider 2 cells, embryos, and adult flies. Paper-114086.
Most small nuclear RNAs (snRNAs) are synthesized by RNA polymerase II, but U6 snRNA is synthesized by RNA polymerase III. Paper-8414022.
We have cloned and sequenced the gene coding for the second-largest subunit of RNA polymerase III of Drosophila melanogaster ( DmRP135). Paper-4618.
High-level activation of transcription of the yeast U6 snRNA gene in chromatin by the basal RNA polymerase III transcription factor TFIIIC. Paper-10249095.
We further show that Myc can control RNA polymerase III independently of Max, which explains some of Myc's observed biological activities. Paper-13535223.
Most small nuclear RNAs (snRNAs) are synthesized by RNA polymerase II, but U6 and a few others are synthesized by RNA polymerase III. Paper-1341743.
In animals, most small nuclear RNAs (snRNAs) are synthesized by RNA polymerase II ( Pol II), but U6 snRNA is synthesized by RNA polymerase III (Pol III). Paper-12424547.
Up to now, it has been thought that the La antigen is associated only with RNAs transcribed by RNA polymerase III, including precursors of tRNA and 5 S ribosomal RNA. Paper-4761047.
Plasmid DNAs containing RNA polymerase III or weak RNA polymerase II promoters are of intermediate rescue efficiency, and pBR322 DNA is least efficient. Paper-5753274.
A subunit of the Drosophila RNA polymerase III transcription factor IIIB ( TFIIIB) complex has been identified using antibodies directed against the analogous human protein, hIIIB90. Paper-1100751.
Most small nuclear RNA ( snRNA) genes are transcribed by RNA polymerase II, but some (e.g., U6) are transcribed by RNA polymerase III. Paper-1316569.
RNA polymerase preparations of D. melanogaster were blotted and the second-largest subunits were identified with antibodies raised against polypeptides expressed from DmRP128 and DmRP135. Paper-41602.
Transcription of the U6 snRNA gene ( SNR6) in Saccharomyces cerevisiae by RNA polymerase III ( pol III) requires TFIIIC and its box A and B binding sites. Paper-10249095.
In vertebrates a TATA box at a fixed distance downstream of the proximal sequence element (PSE) acts as a dominant determinant for recruiting RNA polymerase III to U6 gene promoters. Paper-1316569.
Upstream of the gene coding for the second-largest subunit of RNA polymerase III ( DmRP128) we have found another gene ( 128up), which is transcribed in the same direction as the RNA polymerase gene. Paper-114086.
Examination of the relative activities of TFIIIC showed that both its ability to reconstitute transcription with TFIIIB and RNA polymerase III and its ability to stably bind to the DNA template are unchanged. Paper-7920866.
In its RNA binding and UV cross-linking properties, the endogenous poly(U)-binding protein resembles human La, an autoantigen that binds the U > 3 3' ends of vertebrate RNA polymerase III primary transcripts. Paper-7889879.
The TATA box sequence in eukaryotes is located about 25 bp upstream of many genes transcribed by RNA polymerase II ( Pol II) and some genes transcribed by RNA polymerase III (Pol III). Paper-357237.
In this communication we identify and initially characterize two antagonistic activities in a Xenopus oocyte extract that can modulate the in vitro transcription of RNA polymerase III ( pol III) genes (5 S RNA and tRNA genes). Paper-6816048.
The protein stimulates transcription from the U1 gene promoter by RNA polymerase II and from the U6 gene promoter by RNA polymerase III in Drosophila nuclear extracts, and activation is dependent upon the presence of a PSE. Paper-1176143.
Work from a number of laboratories has indicated that the TATA box sequence can act as a basal promoter element not only for RNA polymerase II ( RNAP II) transcription, but also for transcription by RNA polymerase III ( RNAP III). Paper-657304.
Together, these results indicate that the TPA response in Drosophila cells stimulates specific transcription of RNA polymerase III genes by increasing the activity of the limiting transcription component, TFIIIB, and thereby increasing the number of functional transcription complexes. Paper-7920866.
The Drosophila U6 PSE is incapable of recruiting RNA polymerase II to initiate transcription from the U1 promoter region, and the U1 PSE is unable to recruit RNA polymerase III to transcribe the U6 gene. Paper-9049010.
Thus, HeLa whole-cell lysates contain a specific inhibitor(s) of RNA polymerase III transcription that primarily affects weakened RNA polymerase III promoters (e.g., A-box deletion mutants) and binds preferentially to DNAs containing an active RNA polymerase II promoter. Paper-5753274.
Transcription of genes coding for metazoan spliceosomal snRNAs by RNA polymerase II ( U1, U2, U4, U5) or RNA polymerase III ( U6) is dependent upon a unique, positionally conserved regulatory element referred to as the proximal sequence element (PSE). Paper-9049010.
Experiments with mammalian transcription extracts have led to the proposal that the La protein is required for multiple rounds of transcription by RNA polymerase III (E. Gottlieb and J. A. Steitz, EMBO J. 8:851-861, 1989; R. J. Maraia, D. J. Kenan, and J. D. Keene, Mol. Cell. Biol. 14:2147-2158, 1994). Paper-126388.
The hsp70 promoter, taken from the appropriate heat-shock-protein gene of Drosophila melanogaster, and the VA-1 RNA promoter, derived from the Ad5 gene coding for low-molecular-mass VA-1 RNA and recognized by RNA polymerase III were used as regulatory elements of transcription. Paper-6843436.
However, our in vitro transcription study reveals that transcription from the human L1 promoter is highly sensitive to tagetitoxin, a selective inhibitor of RNA polymerase III ( pol III), but insensitive to 1 micrograms/ml of alpha-amanitin, indicating that the human L1 promoter is pol III-dependent. Paper-385773.
Biochemical studies have revealed La to be a promiscuous RNA- binding protein that appears to play a role in a variety of intracellular activities such as processing and/or transport of RNA polymerase III precursor transcripts and translational regulation from internal ribosome entry sites (IRES). Paper-2173450.
Antibodies directed against a fusion protein expressing 164 amino acids of the DmRP135 polypeptide cross-react with the second-largest subunit of RNA polymerase III of yeast and generate a distinct banding pattern on Drosophila polytene chromosomes distinguishable from that obtained with anti-RNA polymerase II antibodies. Paper-4618.
These synonyms are used for gene RpIII128 (RNA polymerase III 128kD subunit): RP128, RNA polymerase III subunit C2, DNA-directed RNA polymerase III subunit RPC2, DNA-directed RNA polymerase III 128 kDa polypeptide, DmRP128, Dmel\CG8344, CG8344, C128.
These accession numbers are used for gene RpIII128: Q9V649 (UNIPROT__AC), Q8MRD5 (UNIPROT__AC), CAA41631 (NCBI_GENBANK__AC), AAF58590 (NCBI_GENBANK__AC).
RpIII128 is a homologue of rpc2 (DNA-directed RNA polymerase III complex subunit Rpc2) from Schizosaccharomyces pombe.
RpIII128 is a homologue of RET1 (Ret1p) from Saccharomyces cerevisiae.
RpIII128 is a homologue of POLR3B (polymerase (RNA) III (DNA directed) polypeptide B) from Homo sapiens.
RpIII128 is a homologue of POLR3B (polymerase (RNA) III (DNA directed) polypeptide B) from Bos taurus.
RpIII128 is a homologue of POLR3B (polymerase (RNA) III (DNA directed) polypeptide B) from Pan troglodytes.
RpIII128 is a homologue of POLR3B (polymerase (RNA) III (DNA directed) polypeptide B) from Gallus gallus.
RpIII128 is a homologue of POLR3B (polymerase (RNA) III (DNA directed) polypeptide B) from Canis lupus familiaris.
RpIII128 is a homologue of Polr3b (polymerase (RNA) III (DNA directed) polypeptide B) from Mus musculus.
RpIII128 is a homologue of Polr3b (polymerase (RNA) III (DNA directed) polypeptide B) from Rattus norvegicus.
RpIII128 is a homologue of polr3b (polymerase (RNA) III (DNA directed) polypeptide B) from Danio rerio.
RpIII128 is a homologue of PFL0330c (DNA-directed RNA polymerase III subunit) from Plasmodium falciparum 3D7.
RpIII128 is a homologue of Os03g0403100 (Os03g0403100) from Oryza sativa Japonica Group.
RpIII128 is a homologue of NRPC2 (NRPC2; DNA binding / DNA-directed RNA polymerase/ ribonucleoside binding) from Arabidopsis thaliana.
RpIII128 is a homologue of NCU01772 (DNA-directed RNA polymerase III 130 kDa polypeptide) from Neurospora crassa OR74A.
RpIII128 is a homologue of MGG_06984 (hypothetical protein) from Magnaporthe grisea 70-15.
RpIII128 is a homologue of KLLA0F01078g (hypothetical protein) from Kluyveromyces lactis NRRL Y-1140.
RpIII128 is a homologue of F09F7.3 (hypothetical protein) from Caenorhabditis elegans.
RpIII128 is a homologue of AGOS_ADL275C (ADL275Cp) from Ashbya gossypii ATCC 10895.
RpIII128 is a homologue of AgaP_AGAP008151 (AGAP008151-PA) from Anopheles gambiae str. PEST.
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