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Furthermore, branchiomotor neurons were restored in cyclops mutants when shh or twhh was overexpressed. Paper-1639365.
In addition, we show that shh and twhh display both unique and redundant functions during diencephalic patterning. Paper-11310464.
In contrast, proximal fates were lost in cyclops mutant embryos, which lack twhh- and shh-expressing forebrain cells. Paper-403781.
Moreover, TCDD exposure caused downregulation of shha and shhb in a manner dependent on aryl hydrocarbon receptor 2 ( ahr2). Paper-12110254.
Unlike other vertebrates, zebrafish express three hh genes in the embryonic midline: shh, echidna hedgehog ( ehh) and tiggywinkle hedgehog ( twhh). Paper-8946322.
The zebrafish hedgehog (hh) family members tiggy-winkle hedgehog ( twhh) and sonic hedgehog ( shh) are involved in patterning the ventral CNS and proximal eye. Paper-945574.
Here we report that two vertebrate hh genes, sonic hedgehog ( shh) and tiggy-winkle hedgehog ( twhh), may perform similar functions in the developing zebrafish. Paper-2202364.
In cyclops mutants, reduction in sonic hedgehog ( shh) expression, and elimination of tiggy-winkle hedgehog ( twhh) expression, correlated with reductions in branchiomotor neuron populations. Paper-1639365.
Both twhh and shh are expressed in the ventral midline of the embryonic zebrafish neural tube and brain, but twhh expression becomes limited to the neural tube, whereas shh is also expressed in the notochord. Paper-403781.
Furthermore, tri and kny have overlapping functions in establishing proper alignment of the anterior neural plate and midline cells expressing shh and twhh genes when the partitioning of the eye primordium takes place. Paper-1660385.
Both twhh and shh proteins undergo autoproteolytic processing in vivo; a fragment corresponding to the amino-terminal cleavage product was sufficient to carry out all signaling activities associated with twhh in eye and brain development. Paper-403781.
Here, we describe formation of the ZLI in zebrafish in relation to expression of sonic hedgehog ( shh) and tiggy-winkle hedgehog ( twhh), and to development of the forebrain regions that flank the ZLI: the prethalamus and thalamus. Paper-11310464.
We demonstrate that the developing lower jaw expresses sonic hedgehog a ( shha), sonic hedgehog b ( shhb) and their receptors, patched1 ( ptc1) and patched2 ( ptc2), as well as the downstream transcription factors, gli1 and gli2a. Paper-12110254.
Both shh and twhh are expressed in the embryonic zebrafish retinal pigmented epithelium (RPE), initially in a discrete ventral patch which then expands outward in advance of an expanding wave of photoreceptor recruitment in the subjacent neural retina. Paper-2202364.
These synonyms are used for gene shhb (sonic hedgehog b): TWHH, twhh, twh, Tiggy-winkle hedgehog protein, Sonic hedgehog protein B, SHHB.
These accession numbers are used for gene shhb: U30710 (NCBI_GENBANK__AC), Q6DBX7 (UNIPROT__AC), AAC59741 (NCBI_GENBANK__AC), A3KPX7 (UNIPROT__AC).
shhb is a homologue of shha (sonic hedgehog a) from Danio rerio.
shhb is a homologue of SHH (sonic hedgehog homolog (Drosophila)) from Homo sapiens.
shhb is a homologue of SHH (sonic hedgehog homolog (Drosophila)) from Bos taurus.
shhb is a homologue of SHH (sonic hedgehog homolog (Drosophila)) from Pan troglodytes.
shhb is a homologue of SHH (sonic hedgehog homolog (Drosophila)) from Gallus gallus.
shhb is a homologue of SHH (sonic hedgehog homolog (Drosophila)) from Canis lupus familiaris.
shhb is a homologue of Shh (sonic hedgehog) from Mus musculus.
shhb is a homologue of Shh (sonic hedgehog) from Rattus norvegicus.
shhb is a homologue of LOC798440 (sonic hedgehog-like) from Danio rerio.
shhb is a homologue of hh (hedgehog) from Drosophila melanogaster.
shhb is a homologue of AgaP_AGAP001412 (AGAP001412-PA) from Anopheles gambiae str. PEST.
Important links !
iHOP - Information Hyperlinked over Proteins .
Concept & Implementation by Robert Hoffmann.