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The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis. Paper-1055593.
MLD overexpression inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Paper-1055593.
Cotransfection of MLD with the epidermal growth factor ( EGF) receptor resulted in decreased expression of the receptor but did not affect platelet-derived growth factor receptor expression. Paper-1055593.

These synonyms are used for gene DEGS1 (degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)): Sphingolipid delta(4)-desaturase DES1, MLD, MIG15, MGC5079, Membrane lipid desaturase, FADS7, Des-1, DES1, DEGS, Degenerative spermatocyte homolog 1, Cell migration-inducing gene 15 protein.

These accession numbers are used for gene DEGS1: CR614089 (NCBI_GENBANK__AC), CR599325 (NCBI_GENBANK__AC), A8CGI7 (UNIPROT__AC).

DEGS1 is a homologue of F33D4.4 (hypothetical protein) from Caenorhabditis elegans.
DEGS1 is a homologue of DEGS1 (degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)) from Pan troglodytes.
DEGS1 is a homologue of DEGS1 (degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)) from Bos taurus.
DEGS1 is a homologue of DEGS1 (degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)) from Gallus gallus.
DEGS1 is a homologue of DEGS1 (degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)) from Canis lupus familiaris.
DEGS1 is a homologue of Degs1 (degenerative spermatocyte homolog 1 (Drosophila)) from Mus musculus.
DEGS1 is a homologue of Degs1 (degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)) from Rattus norvegicus.
DEGS1 is a homologue of degs1 (degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)) from Danio rerio.

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