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Therefore, SPC12 and SPC25 are likely to be involved in processes other than the enzymatic cleavage of the signal sequence. Paper-547676.
Consistent with being the only SPC subunit with at least one intrachain disulfide bond, SPC 25 contains 4 Cys residues. Paper-135672.
We have determined the cDNA sequence of the remaining 12-kDa subunit ( SPC12) as well as the membrane topologies of SPC12 and SPC25 in rough microsomes. Paper-547676.
RNA interference-mediated depletion of hSPC25 in HeLa cells caused aberrant mitosis, followed by cell death, a phenotype similar to that of cells depleted of HEC1. Paper-10405581.
The maturation of the core protein (C) of Hepatitis C virus ( HCV) is controlled by the signal peptidase ( sp) and signal peptide peptidase ( spp) of the host. Paper-11489346.
These results firmly establish that SPP-catalysed liberation of mature core protein is absolutely dependent on prior cleavage by SP at the correct core-E1 site to generate the complete form of core protein, consistent with this obligatory order of processing playing a role in HCV infectious cycle. Paper-14004849.
To better understand the function of the NDC80 complex, we have identified two novel subunits of the human NDC80 complex, termed human SPC25 ( hSPC25) and human SPC24 (hSPC24), using an immunoaffinity approach. hSPC25 interacted with HEC1 (human homolog of yeast Ndc80) throughout the cell cycle and localized to kinetochores during mitosis. Paper-10405581.
These synonyms are used for gene SPCS2 (signal peptidase complex subunit 2 homolog (S. cerevisiae)): SPC25, SPase 25 kDa subunit, Signal peptidase complex subunit 2, Microsomal signal peptidase 25 kDa subunit, MGC117366, KIAA0102.
These accession numbers are used for gene SPCS2: Q6FG65 (UNIPROT__AC), Q3KQT0 (UNIPROT__AC), AAH70276 (NCBI_GENBANK__AC), AAH08063 (NCBI_GENBANK__AC).
SPCS2 is a homologue of Y37D8A.10 (hypothetical protein) from Caenorhabditis elegans.
SPCS2 is a homologue of SPCS2 (signal peptidase complex subunit 2 homolog (S. cerevisiae)) from Bos taurus.
SPCS2 is a homologue of SPCS2 (signal peptidase complex subunit 2 homolog (S. cerevisiae)) from Pan troglodytes.
SPCS2 is a homologue of SPCS2 (signal peptidase complex subunit 2 homolog (S. cerevisiae)) from Gallus gallus.
SPCS2 is a homologue of SPCS2 (signal peptidase complex subunit 2 homolog (S. cerevisiae)) from Canis lupus familiaris.
SPCS2 is a homologue of Spcs2 (signal peptidase complex subunit 2 homolog (S. cerevisiae)) from Mus musculus.
SPCS2 is a homologue of Spcs2 (signal peptidase complex subunit 2 homolog (S. cerevisiae)) from Rattus norvegicus.
SPCS2 is a homologue of spcs2 (signal peptidase complex subunit 2 homolog (S. cerevisiae)) from Danio rerio.
SPCS2 is a homologue of Spase25 (Spase 25-subunit) from Drosophila melanogaster.
SPCS2 is a homologue of AgaP_AGAP011842 (AGAP011842-PA) from Anopheles gambiae str. PEST.
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