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However, the binding affinities and agonistic activities of H3 agonists to HH4R were weaker than those to HH3R. Paper-8513193.
These observations indicate that the clone is a distinct histamine receptor from HH3R, and thus is named HH4R. Paper-8513193.
Low expression of HH4R was detected in a wide variety of peripheral tissues by RT-PCR; however, in contrast with HH3R, expression was not detected in the brain. Paper-8513193.
METHODS: Ninety-five single nucleotide polymorphisms (SNP) located in eight genes ( CD28, CTLA4, ICOS, ADAM23, ADAMTSL1, MS4A2, CDH26 and HRH3) were genotyped in >5000 individuals from Australian (n = 1162), Dutch (n = 99) and Danish (n = 303) families. Paper-14046935.
These synonyms are used for gene HRH3 (histamine receptor H3): Histamine H3 receptor, HH3R, H3R, G-protein coupled receptor 97, GPCR97.
These accession numbers are used for gene HRH3: Q9GZX2 (UNIPROT__AC), Q4QRI7 (UNIPROT__AC), AF321910 (NCBI_GENBANK__AC), AF140538 (NCBI_GENBANK__AC).
HRH3 is a homologue of LOC100331077 (histamine H3 receptor-like) from Danio rerio.
HRH3 is a homologue of HRH3 (histamine receptor H3) from Canis lupus familiaris.
HRH3 is a homologue of HRH3 (histamine receptor H3) from Bos taurus.
HRH3 is a homologue of HRH3 (histamine receptor H3) from Gallus gallus.
HRH3 is a homologue of Hrh3 (histamine receptor H3) from Mus musculus.
HRH3 is a homologue of Hrh3 (histamine receptor H3) from Rattus norvegicus.
Important links !
iHOP - Information Hyperlinked over Proteins .
Concept & Implementation by Robert Hoffmann.