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Calnexin is not essential for mammalian rod opsin biogenesis. Paper-13520858.
Nucleotide sequence of a Drosophila melanogaster cDNA encoding a calnexin homologue. Paper-1090612.
Calnexin is essential for rhodopsin maturation, Ca2+ regulation, and photoreceptor cell survival. Paper-10826904.
The deduced amino acid sequence shares several regions of homology with Cnx from other sources with two conserved motifs each repeated four times. Paper-1090612.
CONCLUSIONS: Our data show that, unlike Drosophila Rh1, mammalian rod opsin biogenesis does not appear to have an absolute requirement for Cnx. Paper-13520858.
Finally, mutations in calnexin lead to retinal degeneration that is enhanced by light, suggesting that calnexin's function as a Ca2+ buffer is important for photoreceptor cell survival. Paper-10826904.
In addition, we will describe insect and mammalian expression systems in which major histocompatibility complex class I molecules are used as model glycoprotein substrates for CNX and CRT. Paper-10771166.
Our results illustrate a critical role for calnexin in Rh1 maturation and Ca2+ regulation and provide genetic evidence that defects in calnexin lead to retinal degeneration. Paper-10826904.
A 90-kilodalton membrane-bound chaperone of the endoplasmic reticulum (ER), termed calnexin, associates quantitatively with newly synthesized class I heavy chains, but the functions of calnexin in this interaction are unknown. Paper-8215444.
METHODS: Mouse embryonic fibroblasts (MEFs) from control mice (WT) and mice that express a truncated dysfunctional version of Cnx (sCnx) were used to assess the role of Cnx in the biogenesis, maturation, degradation, and aggregation of mutant and wild-type rod opsin. Paper-13520858.
These synonyms are used for gene Cnx99A (Calnexin 99A): Dmel\CG11958, Cnx, CG11958.
These accession numbers are used for gene Cnx99A: .
Cnx99A is a homologue of Os04g0402100 (Os04g0402100) from Oryza sativa Japonica Group.
Cnx99A is a homologue of NCU09265 (similar to calnexin) from Neurospora crassa OR74A.
Cnx99A is a homologue of MGG_01607 (hypothetical protein) from Magnaporthe grisea 70-15.
Cnx99A is a homologue of KLLA0F00462g (hypothetical protein) from Kluyveromyces lactis NRRL Y-1140.
Cnx99A is a homologue of cnx-1 (CalNeXin) from Caenorhabditis elegans.
Cnx99A is a homologue of cnx1 (calnexin (PMID 7876257)) from Schizosaccharomyces pombe.
Cnx99A is a homologue of CNE1 (Calnexin; integral membrane ER chaperone involved in folding and quality...) from Saccharomyces cerevisiae.
Cnx99A is a homologue of CG9906 (CG9906 gene product from transcript CG9906-RA) from Drosophila melanogaster.
Cnx99A is a homologue of CG1924 (CG1924 gene product from transcript CG1924-RA) from Drosophila melanogaster.
Cnx99A is a homologue of CANX (calnexin) from Homo sapiens.
Cnx99A is a homologue of CANX (calnexin) from Pan troglodytes.
Cnx99A is a homologue of CANX (calnexin) from Gallus gallus.
Cnx99A is a homologue of CANX (calnexin) from Canis lupus familiaris.
Cnx99A is a homologue of Canx (calnexin) from Mus musculus.
Cnx99A is a homologue of Canx (calnexin) from Rattus norvegicus.
Cnx99A is a homologue of canx (calnexin) from Danio rerio.
Cnx99A is a homologue of AT5G61790 (calnexin 1 (CNX1)) from Arabidopsis thaliana.
Cnx99A is a homologue of AT5G07340 (calnexin, putative) from Arabidopsis thaliana.
Cnx99A is a homologue of AgaP_AGAP005032 (AGAP005032-PA) from Anopheles gambiae str. PEST.
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iHOP - Information Hyperlinked over Proteins .
Concept & Implementation by Robert Hoffmann.