Click here for the function of HTR1F.
Edit this page in Wiki Genes - HTR1F or see Wiki Gene.
Sequencing of two positional candidate genes, 5HT1F and DRD3, did not support their role in dyslexia. Paper-9111487.
5-Hydroxyptryptamine 1F ( 5-HT1F) receptor agonism. A possible new treatment principle for acute migraine attacks. Paper-15416020.
HeLa cells transfected with the MR77 gene exhibited inhibition of adenylate cyclase in response to serotonin. Paper-7780663.
MR77 is expressed at low levels throughout the brain, with the greatest expression in the cortex, hippocampus, and striatum. Paper-7780663.
Cloning of another human serotonin receptor ( 5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase. Paper-7648109.
Chromosomal localization of the 5-HT1F receptor gene: no evidence for involvement in response to sumatriptan in migraine patients. Paper-1707557.
The 5-HT1F receptor, which is present in both human vascular and neuronal tissue, may mediate the therapeutic effect and/or side-effects of sumatriptan. Paper-1707557.
We therefore conclude that genetic diversity of the 5-HT1F receptor gene is most probably not responsible for the variable clinical response to sumatriptan. Paper-1707557.
In conclusion, our studydoes not provide evidence that the 5HTT, 5-HT1A, 5HT1B,5HT2A and 5HT6 gene polymorphisms play a role in the genetic predisposition to MOH. Paper-14216691.
MR77 thus represents a 5-HT receptor of the 5-HT1 class, and we propose that, based on the pharmacological characterization, MR77 represents an additional 5-HT1E-like receptor. Paper-7780663.
We investigated the chromosomal localization of the 5-HT1F receptor gene and the relation between eventually existing polymorphisms and the clinical response to sumatriptan in migraine patients. Paper-1707557.
The resulting product was subcloned and used to screen a rat genomic library to identify a full-length clone ( MR77) containing an intronless open reading frame encoding a 366-amino acid seven-transmembrane domain protein. Paper-7780663.
These synonyms are used for gene HTR1F (5-hydroxytryptamine (serotonin) receptor 1F): Serotonin receptor 1F, MR77, HTR1EL, 5-hydroxytryptamine receptor 1F, 5HT6, 5-HT-1F, 5-HT1F.
These accession numbers are used for gene HTR1F: Q9P2Q4 (UNIPROT__AC), BC096838 (NCBI_GENBANK__AC), AF498981 (NCBI_GENBANK__AC).
HTR1F is a homologue of LOC100005344 (5-hydroxytryptamine (serotonin) receptor 1F-like) from Danio rerio.
HTR1F is a homologue of HTR1F (5-hydroxytryptamine (serotonin) receptor 1F) from Pan troglodytes.
HTR1F is a homologue of HTR1F (5-hydroxytryptamine (serotonin) receptor 1F) from Bos taurus.
HTR1F is a homologue of HTR1F (5-hydroxytryptamine (serotonin) receptor 1F) from Gallus gallus.
HTR1F is a homologue of Htr1f (5-hydroxytryptamine (serotonin) receptor 1F) from Mus musculus.
HTR1F is a homologue of Htr1f (5-hydroxytryptamine (serotonin) receptor 1F) from Rattus norvegicus.
Important links !
iHOP - Information Hyperlinked over Proteins .
Concept & Implementation by Robert Hoffmann.