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At the cellular level, transcripts encoding RNase k6 were detected in normal human monocytes and neutrophils (but not in eosinophils) suggesting a role for this ribonuclease in host defense. Paper-700910.
Of the five previously identified human ribonucleases of this group, RNase k6 is most closely related to eosinophil-derived neurotoxin ( EDN), with 47% amino acid sequence identity; slight cross-reactivity between RNase k6 and EDN was observed on Western blots probed with polyclonal anti- EDN antiserum. Paper-700910.
These synonyms are used for gene RNASE6 (ribonuclease, RNase A family, k6): RNS6, RNase K6, RNasek6, Ribonuclease K6.
These accession numbers are used for gene RNASE6: Q6IB39 (UNIPROT__AC), AAH20848 (NCBI_GENBANK__AC), AAC51848 (NCBI_GENBANK__AC).
RNASE6 is a homologue of RNASE6 (ribonuclease, RNase A family, k6) from Pan troglodytes.
RNASE6 is a homologue of RNASE6 (ribonuclease, RNase A family, k6) from Bos taurus.
RNASE6 is a homologue of Rnase6 (ribonuclease, RNase A family, 6) from Mus musculus.
RNASE6 is a homologue of Rnase6 (ribonuclease, RNase A family, 6) from Rattus norvegicus.
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